A Mechanism of Unidirectional Transformation, Leading to Antibiotic Resistance, Occurs within Nasopharyngeal Pneumococcal Biofilm Consortia

A Mechanism of Unidirectional Transformation, Leading to Antibiotic Resistance, Occurs within Nasopharyngeal Pneumococcal Biofilm Consortia

Streptococcus pneumoniae acquires genes for resistance to antibiotics such as streptomycin (Str) or trimethoprim (Tmp) by recombination via transformation of DNA released by other pneumococci and closely related species. Using naturally transformable pneumococci, including strain D39 serotype 2 (S2)...

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Bibliographic Details
Main Authors: Santiago M. Lattar, Xueqing Wu, Jennifer Brophy, Fuminori Sakai, Keith P. Klugman, Jorge E. Vidal
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
Streptococcus pneumoniae
antibiotic resistance
consortial biofilms
unidirectional transformation
Online Access:https://doi.org/10.1128/mBio.00561-18

Internet

https://doi.org/10.1128/mBio.00561-18

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