Rapid identification of malaria vaccine candidates based on alpha-helical coiled coil protein motif.
To identify malaria antigens for vaccine development, we selected alpha-helical coiled coil domains of proteins predicted to be present in the parasite erythrocytic stage. The corresponding synthetic peptides are expected to mimic structurally "native" epitopes. Indeed the 95 chemically sy...
Main Authors: | , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2007-07-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0000645 |