A unified route for flavivirus structures uncovers essential pocket factors conserved across pathogenic viruses

Understanding virus assembly could identify potential drug targets. Here the authors use a safe and efficient method to solve pathogenic flavivirus structures, revealing two lipid-like ligands within highly conserved pockets of the stem region of envelope protein that are important for virus maturat...

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Bibliographic Details
Main Authors: Joshua M. Hardy, Natalee D. Newton, Naphak Modhiran, Connor A. P. Scott, Hariprasad Venugopal, Laura J. Vet, Paul R. Young, Roy A. Hall, Jody Hobson-Peters, Fasséli Coulibaly, Daniel Watterson
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22773-1