LIN28a induced metabolic and redox regulation promotes cardiac cell survival in the heart after ischemic injury

LIN28a induced metabolic and redox regulation promotes cardiac cell survival in the heart after ischemic injury

Rationale: Cell-based therapeutics have been extensively used for cardiac repair yet underperform due to inability of the donated cells to survive in near anoxia after cardiac injury. Cellular metabolism is linked to maintenance of cardiac stem cell (CSC) renewal, proliferation and survival. Ex vivo...

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Bibliographic Details
Main Authors: Antonia Elizabeth Yuko, Vagner Oliveira Carvalho Rigaud, Justin Kurian, Ji H. Lee, Nicole Kasatkin, Michael Behanan, Tao Wang, Anna Maria Luchesse, Sadia Mohsin, Walter J. Koch, Hong Wang, Mohsin Khan
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Redox Biology
Subjects:
Metabolism
Myocardial ischemia
Cell therapy
Redox regulation
Survival
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721003220

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http://www.sciencedirect.com/science/article/pii/S2213231721003220

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