Exhausting circ_0136474 and Restoring miR-766-3p Attenuate Chondrocyte Oxidative Injury in IL-1β-Induced Osteoarthritis Progression Through Regulating DNMT3A

Exhausting circ_0136474 and Restoring miR-766-3p Attenuate Chondrocyte Oxidative Injury in IL-1β-Induced Osteoarthritis Progression Through Regulating DNMT3A

Circular RNA circ_0136474 is a new contributor of human osteoarthritis (OA) by suppressing chondrocyte proliferation. However, its role and mechanism in OA chondrocyte injury remain ill defined. Herein, we performed real-time quantitative PCR to detect RNA expression of circ_0136474, microRNA (miR)-...

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Bibliographic Details
Main Authors: Haiquan Zhu, Shaobo Zhu, Xiuchao Shang, Xiangsheng Meng, Sheng Jing, Li Yu, Yu Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Genetics
Subjects:
circ_0136474
miR-766-3p
DNMT3A
chondrocytes
osteoarthritis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.648709/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.648709/full

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