Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels.

Vector-borne diseases such as dengue fever and malaria, which are transmitted by infected female mosquitoes, affect nearly half of the world's population. The emergence of insecticide-resistant mosquito populations is reducing the effectiveness of conventional insecticides and threatening curre...

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Bibliographic Details
Main Authors: Rene Raphemot, Matthew F Rouhier, Daniel R Swale, Emily Days, C David Weaver, Kimberly M Lovell, Leah C Konkel, Darren W Engers, Sean R Bollinger, Corey Hopkins, Peter M Piermarini, Jerod S Denton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4222822?pdf=render