A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA

A DNA Methylation-Based Test for Breast Cancer Detection in Circulating Cell-Free DNA

Background: Breast cancer (BrC) is the most frequent neoplasm in women. New biomarkers, including aberrant DNA methylation, may improve BrC management. Herein, we evaluated the detection and prognostic performance of seven genes&#8217; promoter methylation (<i>APC</i>, <i>BRCA1...

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Bibliographic Details
Main Authors: Sofia Salta, Sandra P. Nunes, Mário Fontes-Sousa, Paula Lopes, Micaela Freitas, Margarida Caldas, Luís Antunes, Fernando Castro, Pedro Antunes, Susana Palma de Sousa, Rui Henrique, Carmen Jerónimo
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Journal of Clinical Medicine
Subjects:
breast cancer
DNA methylation
epigenetic biomarker
Cell-free DNA
liquid biopsy
diagnosis
prognosis
Online Access:https://www.mdpi.com/2077-0383/7/11/420

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https://www.mdpi.com/2077-0383/7/11/420

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