Regiospecific and Enantiospecific Ring Opening of Methyl (+)-(1'R, 2R)- and (-)-(1'R, 2S)-1-(2-phenylethanol) Aziridine-2-carboxylates

Regiospecific and Enantiospecific Ring Opening of Methyl (+)-(1'R, 2R)- and (-)-(1'R, 2S)-1-(2-phenylethanol) Aziridine-2-carboxylates

The acid-catalyzed ring-opening of methyl (+)-(1'R, 2R) and (-)-(1'R, 2S)-1-(2-phenylethanol) aziridine-2-carboxylates (1) and (2) lead quantitatively to the corresponding 2(S)-(-)-chloro-3-[2'-hydroxy-1'(R)-phenyl-ethylamino] propionic acid methyl ester (3) and 2(R)-(-)-chloro-3...

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Bibliographic Details
Main Authors: W. F. Reynolds, R. A. Toscano, Raúl G. Enríquez, Alberto Galindo, Laura F. Orea, Dino Gnecco
Format: Article
Language:English
Published: MDPI AG 2000-08-01
Series:Molecules
Subjects:
aziridine-ring opening
regiospecificity
enantiospecificity
Online Access:http://www.mdpi.com/1420-3049/5/8/998/

Internet

http://www.mdpi.com/1420-3049/5/8/998/

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