Plasma Hyperosmolality Prolongs QTc Interval and Increases Risk for Atrial Fibrillation in Traumatic Brain Injury Patients

Plasma Hyperosmolality Prolongs QTc Interval and Increases Risk for Atrial Fibrillation in Traumatic Brain Injury Patients

<b> </b>Introduction: Hyperosmotic therapy with mannitol is frequently used for treatment cerebral edema, and 320 mOsm/kg H<sub>2</sub>O has been recommended as a high limit for therapeutic plasma osmolality. However, plasma hyperosmolality may impair cardiac function, increa...

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Bibliographic Details
Main Authors: Wojciech Dabrowski, Dorota Siwicka-Gieroba, Chiara Robba, Rafael Badenes, Mateusz Bialy, Paulina Iwaniuk, Todd T Schlegel, Andrzej Jaroszynski
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Journal of Clinical Medicine
Subjects:
traumatic brain injury
cardiac arrhythmias
plasma osmolality
osmolar gap
electrocardiography
Online Access:https://www.mdpi.com/2077-0383/9/5/1293

Internet

https://www.mdpi.com/2077-0383/9/5/1293

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