Tyrosine kinase inhibitors for EGFR- and ALK-mutated non-small cell lung cancer

Discovery of the epidermal growth receptor (EGFR) activating mutations and anaplastic lymphoma kinase (ALK) rearrangements has expanded the therapeutic landscape in non-small cell lung cancer (NSCLC). Survival outcomes for patients with these mutations have improved dramatically with EGFR and ALK ty...

Full description

Bibliographic Details
Main Authors: Jonathan R. Thompson, Smitha P. Menon, Grace K. Dy
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2016-10-01
Series:ADMET and DMPK
Subjects:
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/337