Carnosol induces ROS-mediated beclin1-independent autophagy and apoptosis in triple negative breast cancer.

Carnosol induces ROS-mediated beclin1-independent autophagy and apoptosis in triple negative breast cancer.

BACKGROUND:In this study we investigated the in vitro and in vivo anticancer effect of carnosol, a naturally occurring polyphenol, in triple negative breast cancer. RESULTS:We found that carnosol significantly inhibited the viability and colony growth induced G2 arrest in the triple negative MDA-MB-...

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Bibliographic Details
Main Authors: Yusra Al Dhaheri, Samir Attoub, Gaber Ramadan, Kholoud Arafat, Khuloud Bajbouj, Noushad Karuvantevida, Synan AbuQamar, Ali Eid, Rabah Iratni
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4192122?pdf=render

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http://europepmc.org/articles/PMC4192122?pdf=render

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