Role of nanoparticle size and sialic acids in the distinct time-evolution profiles of nanoparticle uptake in hematopoietic progenitor cells and monocytes

Role of nanoparticle size and sialic acids in the distinct time-evolution profiles of nanoparticle uptake in hematopoietic progenitor cells and monocytes

Abstract Background Human hematopoietic progenitor cells (HPCs) are important for cell therapy in cancer and tissue regeneration. In vitro studies have shown a transient association of 40 nm polystyrene nanoparticles (PS NPs) with these cells, which is of interest for intelligent design and applicat...

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Bibliographic Details
Main Authors: Bart Wathiong, Sarah Deville, An Jacobs, Nick Smisdom, Pascal Gervois, Ivo Lambrichts, Marcel Ameloot, Jef Hooyberghs, Inge Nelissen
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Nanobiotechnology
Subjects:
Nanoparticles
Hematopoietic progenitor cells
Monocytes
Flow cytometry
Confocal imaging
Proteoglycans
Online Access:http://link.springer.com/article/10.1186/s12951-019-0495-x

Internet

http://link.springer.com/article/10.1186/s12951-019-0495-x

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