Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers

Differential Expression of ADP/ATP Carriers as a Biomarker of Metabolic Remodeling and Survival in Kidney Cancers

ADP/ATP carriers (AACs) are mitochondrial transport proteins playing a strategic role in maintaining the respiratory chain activity, fueling the cell with ATP, and also regulating mitochondrial apoptosis. To understand if AACs might represent a new molecular target for cancer treatment, we evaluated...

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Bibliographic Details
Main Authors: Lucia Trisolini, Luna Laera, Maria Favia, Antonella Muscella, Alessandra Castegna, Vito Pesce, Lorenzo Guerra, Anna De Grassi, Mariateresa Volpicella, Ciro Leonardo Pierri
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomolecules
Subjects:
ADP/ATP carriers (AACs)
SLC25A family
mitochondrial apoptosis
mitochondrial permeability transition pore (mPTP)
kidney cancer
biomarkers of survival
Online Access:https://www.mdpi.com/2218-273X/11/1/38

Internet

https://www.mdpi.com/2218-273X/11/1/38

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