Multi-Omics and Targeted Approaches to Determine the Role of Cellular Proteases in Streptomyces Protein Secretion

Multi-Omics and Targeted Approaches to Determine the Role of Cellular Proteases in Streptomyces Protein Secretion

Gram-positive Streptomyces bacteria are profuse secretors of polypeptides using complex, yet unknown mechanisms. Many of their secretory proteins are proteases that play important roles in the acquisition of amino acids from the environment. Other proteases regulate cellular proteostasis. To begin d...

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Bibliographic Details
Main Authors: Tobias Busche, Konstantinos C. Tsolis, Joachim Koepff, Yuriy Rebets, Christian Rückert, Mohamed B. Hamed, Arne Bleidt, Wolfgang Wiechert, Mariia Lopatniuk, Ahmed Yousra, Jozef Anné, Spyridoula Karamanou, Marco Oldiges, Jörn Kalinowski, Andriy Luzhetskyy, Anastassios Economou
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Microbiology
Subjects:
proteases
expression levels
mRFP
multi-omics
Streptomyces lividans
protein secretion
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.01174/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.01174/full

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