RU486 Reverses Emotional Disorders by Influencing Astrocytes and Endoplasmic Reticulum Stress in Chronic Restraint Stress Challenged Rats

RU486 Reverses Emotional Disorders by Influencing Astrocytes and Endoplasmic Reticulum Stress in Chronic Restraint Stress Challenged Rats

Aims: To investigate the effect of RU486 (mifepristone) on emotional disorders in chronic restraint stress-induced rats and to explore the mechanisms of that phenomenon. Methods: For this purpose, 80 healthy male Sprague Dawley rats were randomly divided into four groups: the normal group (Con group...

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Bibliographic Details
Main Authors: Liru Dong, Songjun Wang, Yingmin Li, Ziqin Zhao, Yiwen Shen, Li Liu, Guangming Xu, Chunling Ma, Shujin Li, Xiaojing Zhang, Bin Cong
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Chronic
Restraint Stress
Astrocyte
Apoptosis
RU486
Endoplasmic Reticulum (ER) Stress
Online Access:http://www.karger.com/Article/FullText/478764

Internet

http://www.karger.com/Article/FullText/478764

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