Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer’s disease
Abstract Background To investigate how serum neurofilament light (NfL) concentration changes through the course of disease in familial Alzheimer’s disease (FAD) and to assess when NfL concentration first increases. Methods NfL was measured using an ultrasensitive immunoassay in 117 serum samples fro...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2019-02-01
|
Series: | Alzheimer’s Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13195-019-0472-5 |