Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer’s disease

Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer’s disease

Abstract Background To investigate how serum neurofilament light (NfL) concentration changes through the course of disease in familial Alzheimer’s disease (FAD) and to assess when NfL concentration first increases. Methods NfL was measured using an ultrasensitive immunoassay in 117 serum samples fro...

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Bibliographic Details
Main Authors: Philip S. J. Weston, Teresa Poole, Antoinette O’Connor, Amanda Heslegrave, Natalie S. Ryan, Yuying Liang, Ronald Druyeh, Simon Mead, Kaj Blennow, Jonathan M. Schott, Chris Frost, Henrik Zetterberg, Nick C. Fox
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Alzheimer’s Research & Therapy
Subjects:
Search terms
[26] Alzheimer’s disease
[91] autosomal dominant
[111] neurofilament light
[111] blood
[111] longitudinal
Online Access:http://link.springer.com/article/10.1186/s13195-019-0472-5

Internet

http://link.springer.com/article/10.1186/s13195-019-0472-5

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