Optimization of the <em> apolipoprotein B mRNA editing enzyme catalytic polypeptidelike-3G </em> (<em>APOBEC3G</em>) gene to enhance its expression in <em> Escherichia coli </em>

Optimization of the <em> apolipoprotein B mRNA editing enzyme catalytic polypeptidelike-3G </em> (<em>APOBEC3G</em>) gene to enhance its expression in <em> Escherichia coli </em>

BACKGROUND Apolipoprotein B mRNA editing enzyme catalytic polypeptide-like-3G (APOBEC3G) can abolish HIV infection by inducing lethal mutations in the HIV genome. The HIV protein virion infectivity factor (Vif) can interact with APOBEC3G protein and cause its degradation. Development of a method th...

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Bibliographic Details
Main Authors: Rizkyana Avissa, Silvia Tri Widyaningtyas, Budiman Bela
Format: Article
Language:English
Published: Faculty of Medicine Universitas Indonesia 2020-06-01
Series:Medical Journal of Indonesia
Subjects:
APOBEC3G
codon usage
prokaryote gene expression
Online Access:https://mji.ui.ac.id/journal/index.php/mji/article/view/2853

Internet

https://mji.ui.ac.id/journal/index.php/mji/article/view/2853

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