Mineral-Doped Poly(L-lactide) Acid Scaffolds Enriched with Exosomes Improve Osteogenic Commitment of Human Adipose-Derived Mesenchymal Stem Cells

Mineral-Doped Poly(L-lactide) Acid Scaffolds Enriched with Exosomes Improve Osteogenic Commitment of Human Adipose-Derived Mesenchymal Stem Cells

Exosomes derived from mesenchymal stem cells are extracellular vesicles released to facilitate cell communication and function. Recently, polylactic acid (PLA), calcium silicates (CaSi), and dicalcium phosphate dihydrate (DCPD) have been used to produce bioresorbable functional mineral-doped porous...

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Bibliographic Details
Main Authors: Maria Giovanna Gandolfi, Chiara Gardin, Fausto Zamparini, Letizia Ferroni, Micaela Degli Esposti, Greta Parchi, Batur Ercan, Lucia Manzoli, Fabio Fava, Paola Fabbri, Carlo Prati, Barbara Zavan
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Nanomaterials
Subjects:
exosomes
human adipose mesenchymal stem cells (had-mscs), polylactic acid scaffold
calcium silicates
exosome enriched scaffolds
regenerative bone healing
green bioplastics
bioresorbable scaffold
natural nanovesicles
nanodelivery
personalized regenerative medicine.
Online Access:https://www.mdpi.com/2079-4991/10/3/432

Internet

https://www.mdpi.com/2079-4991/10/3/432

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