Transcriptional Regulation of the Fetal Cardiac Gene Program

Reactivation of the fetal cardiac gene program in adults is a reliable marker of cardiac hypertrophy and heart failure. Normally, genes within this group are expressed in the fetal ventricles during development, but are silent after birth. However, their expression is re-induced in the ventricular m...

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Bibliographic Details
Main Authors: Koichiro Kuwahara, Toshio Nishikimi, Kazuwa Nakao
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S134786131930489X