Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats

Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats

Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic hepatic disorder worldwide. The earliest stage of NAFLD is simple steatosis, which is characterized by the accumulation of triglycerides in hepatocytes. Inhibition of steatosis is a potential treatment for NAFLD. Patchouli...

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Bibliographic Details
Main Authors: Xue Wu, Nan Xu, Minyao Li, Qionghui Huang, Jiazhen Wu, Yuxuan Gan, Liping Chen, Huijuan Luo, Yucui Li, Xiaoqi Huang, Ziren Su, Yuhong Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Pharmacology
Subjects:
patchouli alcohol
nonalcoholic fatty liver disease
hepatic steatosis
very low-density lipoprotein
endoplasmic reticulum stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.01134/full

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https://www.frontiersin.org/article/10.3389/fphar.2019.01134/full

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