Efflux pump gene expression in multidrug-resistant Mycobacterium tuberculosis clinical isolates.

Isoniazid (INH) and rifampicin (RIF) are the two most effective drugs in tuberculosis therapy. Understanding the molecular mechanisms of resistance to these two drugs is essential to quickly diagnose multidrug-resistant (MDR) tuberculosis and extensive drug-resistant tuberculosis. Nine clinical Myco...

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Bibliographic Details
Main Authors: Guilian Li, Jingrui Zhang, Qian Guo, Yi Jiang, Jianhao Wei, Li-li Zhao, Xiuqin Zhao, Jianxin Lu, Kanglin Wan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4335044?pdf=render