Carbohydrate recognition by an architecturally complex α-N-acetylglucosaminidase from Clostridium perfringens.

CpGH89 is a large multimodular enzyme produced by the human and animal pathogen Clostridium perfringens. The catalytic activity of this exo-α-D-N-acetylglucosaminidase is directed towards a rare carbohydrate motif, N-acetyl-β-D-glucosamine-α-1,4-D-galactose, which is displayed on the class III mucin...

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Bibliographic Details
Main Authors: Elizabeth Ficko-Blean, Christopher P Stuart, Michael D Suits, Melissa Cid, Matthew Tessier, Robert J Woods, Alisdair B Boraston
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3313936?pdf=render