Alterations of adiponectin gene expression and DNA methylation in adipose tissues and blood cells are associated with gestational diabetes and neonatal outcome

Alterations of adiponectin gene expression and DNA methylation in adipose tissues and blood cells are associated with gestational diabetes and neonatal outcome

Abstract Background Adiponectin critically contributes to metabolic homeostasis, especially by insulin-sensitizing action. Gestational diabetes mellitus (GDM) is characterized by insulin resistance leading to materno-fetal hyperglycemia and detrimental birth outcomes. By investigating paired subcuta...

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Bibliographic Details
Main Authors: Raffael Ott, Jens H. Stupin, Kerstin Melchior, Karen Schellong, Thomas Ziska, Joachim W. Dudenhausen, Wolfgang Henrich, Rebecca C. Rancourt, Andreas Plagemann
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Clinical Epigenetics
Subjects:
Gestational diabetes mellitus
Epigenetics
DNA methylation
Adiponectin
Adipose tissue
Blood cells
Online Access:http://link.springer.com/article/10.1186/s13148-018-0567-z

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http://link.springer.com/article/10.1186/s13148-018-0567-z

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