A Non-invasive Platform for Functional Characterization of Stem-Cell-Derived Cardiomyocytes with Applications in Cardiotoxicity Testing

A Non-invasive Platform for Functional Characterization of Stem-Cell-Derived Cardiomyocytes with Applications in Cardiotoxicity Testing

We present a non-invasive method to characterize the function of pluripotent stem-cell-derived cardiomyocytes based on video microscopy and image analysis. The platform, called Pulse, generates automated measurements of beating frequency, beat duration, amplitude, and beat-to-beat variation based on...

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Bibliographic Details
Main Authors: Mahnaz Maddah, Julia D. Heidmann, Mohammad A. Mandegar, Chase D. Walker, Sara Bolouki, Bruce R. Conklin, Kevin E. Loewke
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115000636

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http://www.sciencedirect.com/science/article/pii/S2213671115000636

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