EBV persistence without its EBNA3A and 3C oncogenes in vivo.

The oncogenic Epstein Barr virus (EBV) infects the majority of the human population and usually persists within its host for life without symptoms. The EBV oncoproteins nuclear antigen 3A (EBNA3A) and 3C (EBNA3C) are required for B cell transformation in vitro and are expressed in EBV associated imm...

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Bibliographic Details
Main Authors: Anita Murer, Donal McHugh, Nicole Caduff, Jens Kalchschmidt, Mario Barros, Andrea Zbinden, Riccarda Capaul, Gerald Niedobitek, Martin Allday, Obinna Chijioke, Christian Münz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-04-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007039