Humanized Mouse as a Tool to Predict Immunotoxicity of Human Biologics

Humanized Mouse as a Tool to Predict Immunotoxicity of Human Biologics

Advancements in science enable researchers to constantly innovate and create novel biologics. However, the use of non-human animal models during the development of biologics impedes identification of precise in vivo interactions between the human immune system and treatments. Due to lack of this und...

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Bibliographic Details
Main Authors: Kylie Su Mei Yong, Zhisheng Her, Sue Yee Tan, Wilson Wei Sheng Tan, Min Liu, Fritz Lai, Shi Min Heng, Yong Fan, Kenneth Tou En Chang, Cheng-I Wang, Jerry Kok Yen Chan, Jianzhu Chen, Qingfeng Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Immunology
Subjects:
cytokine storm
biologic testing
humanized mice
immunotoxicity
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.553362/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.553362/full

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