Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis.

Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis.

The majority of nucleotide binding domain leucine rich repeats-containing (NLR) family members has yet to be functionally characterized. Of the described NLRs, most are considered to be proinflammatory and facilitate IL-1β production. However, a newly defined sub-group of NLRs that function as negat...

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Bibliographic Details
Main Authors: Irving C Allen, Erin McElvania-TeKippe, Justin E Wilson, John D Lich, Janelle C Arthur, Jonathan T Sullivan, Miriam Braunstein, Jenny P Y Ting
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3618512?pdf=render

Internet

http://europepmc.org/articles/PMC3618512?pdf=render

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