Living on three time scales: the dynamics of plasma cell and antibody populations illustrated for hepatitis a virus.

Understanding the mechanisms involved in long-term persistence of humoral immunity after natural infection or vaccination is challenging and crucial for further research in immunology, vaccine development as well as health policy. Long-lived plasma cells, which have recently been shown to reside in...

Full description

Bibliographic Details
Main Authors: Mathieu Andraud, Olivier Lejeune, Jammbe Z Musoro, Benson Ogunjimi, Philippe Beutels, Niel Hens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3291529?pdf=render