Living on three time scales: the dynamics of plasma cell and antibody populations illustrated for hepatitis a virus.
Understanding the mechanisms involved in long-term persistence of humoral immunity after natural infection or vaccination is challenging and crucial for further research in immunology, vaccine development as well as health policy. Long-lived plasma cells, which have recently been shown to reside in...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC3291529?pdf=render |