Gut neurotoxin p-cresol induces differential expression of GLUN2B and GLUN2A subunits of the NMDA receptor in the hippocampus and nucleus accumbens in healthy and audiogenic seizure-prone rats

Gut neurotoxin p-cresol induces differential expression of GLUN2B and GLUN2A subunits of the NMDA receptor in the hippocampus and nucleus accumbens in healthy and audiogenic seizure-prone rats

Mislocalization and abnormal expression of N-methyl-D-aspartate glutamate receptor (NMDAR) subunits is observed in several brain disorders and pathological conditions. Recently, we have shown that intraperitoneal injection of the gut neurotoxin p-cresol induces autism-like behavior and accelerates s...

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Bibliographic Details
Main Authors: Gigi Tevzadze, Elene Zhuravliova, Tamar Barbakadze, Lali Shanshiashvili, Davit Dzneladze, Zaqaria Nanobashvili, Tamar Lordkipanidze, David Mikeladze
Format: Article
Language:English
Published: AIMS Press 2020-05-01
Series:AIMS Neuroscience
Subjects:
nmda receptor
p-cresol
epilepsy
nucleus accumbens
hippocampus
Online Access:https://www.aimspress.com/article/10.3934/Neuroscience.2020003/fulltext.html

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https://www.aimspress.com/article/10.3934/Neuroscience.2020003/fulltext.html

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