The phylogeny of 48 alleles, experimentally verified at 21 kb, and its application to clinical allele detection

The phylogeny of 48 alleles, experimentally verified at 21 kb, and its application to clinical allele detection

Abstract Background Sequence information generated from next generation sequencing is often computationally phased using haplotype-phasing algorithms. Utilizing experimentally derived allele or haplotype information improves this prediction, as routinely used in HLA typing. We recently established a...

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Bibliographic Details
Main Authors: Kshitij Srivastava, Kurt R. Wollenberg, Willy A. Flegel
Format: Article
Language:English
Published: BMC 2019-02-01
Series:Journal of Translational Medicine
Subjects:
Allele prediction
Next generation sequencing
Phylogeny
Scianna
ERMAP
Online Access:http://link.springer.com/article/10.1186/s12967-019-1791-9

Internet

http://link.springer.com/article/10.1186/s12967-019-1791-9

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