Plasma pharmacokinetics and urinary excretion of tenofovir following cessation in adults with controlled levels of adherence to tenofovir disoproxil fumarate

Plasma pharmacokinetics and urinary excretion of tenofovir following cessation in adults with controlled levels of adherence to tenofovir disoproxil fumarate

Objectives: The aim was to fully characterize the plasma and urine washout pharmacokinetics of tenofovir (TFV) in adults following 6 weeks of controlled levels of tenofovir disoproxil fumarate (TDF) adherence, in order to inform the utility of clinic-based adherence testing. Design: This was a three...

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Bibliographic Details
Main Authors: Tim R. Cressey, Oraphan Siriprakaisil, Rachel W. Kubiak, Virat Klinbuayaem, Pra-ornsuda Sukrakanchana, Justice Quame-Amaglo, Hideaki Okochi, Yardpiroon Tawon, Ratchada Cressey, Jared M. Baeten, Monica Gandhi, Paul K. Drain
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:International Journal of Infectious Diseases
Subjects:
HIV
Pre-exposure prophylaxis (PrEP)
Tenofovir
Urine
Plasma
Pharmacokinetics
Online Access:http://www.sciencedirect.com/science/article/pii/S1201971220304720

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http://www.sciencedirect.com/science/article/pii/S1201971220304720

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