A Heterologous Multiepitope DNA Prime/Recombinant Protein Boost Immunisation Strategy for the Development of an Antiserum against Micrurus corallinus (Coral Snake) Venom.

BACKGROUND:Envenoming by coral snakes (Elapidae: Micrurus), although not abundant, represent a serious health threat in the Americas, especially because antivenoms are scarce. The development of adequate amounts of antielapidic serum for the treatment of accidents caused by snakes like Micrurus cora...

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Main Authors: Henrique Roman Ramos, Inácio de Loiola M Junqueira-de-Azevedo, Juliana Branco Novo, Karen Castro, Clara Guerra Duarte, Ricardo A Machado-de-Ávila, Carlos Chavez-Olortegui, Paulo Lee Ho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4777291?pdf=render