The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

Most of peroxisomal matrix proteins including a hydrogen peroxide (H2O2)-decomposing enzyme, catalase, are imported in a peroxisome-targeting signal type-1 (PTS1)-dependent manner. However, little is known about regulation of the membrane-bound protein import machinery. Here, we report that Pex14, a...

Full description

Bibliographic Details
Main Authors: Kanji Okumoto, Mahmoud El Shermely, Masanao Natsui, Hidetaka Kosako, Ryuichi Natsuyama, Toshihiro Marutani, Yukio Fujiki
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
catalase
Pex14
peroxisomal protein import
phosphorylation
hydrogen peroxide
oxidative stress
Online Access:https://elifesciences.org/articles/55896

Internet

https://elifesciences.org/articles/55896

Similar Items