Analysis of Adenoviral p53 Gene Therapy Clinical Trials in Recurrent Head and Neck Squamous Cell Carcinoma

Analysis of Adenoviral p53 Gene Therapy Clinical Trials in Recurrent Head and Neck Squamous Cell Carcinoma

BackgroundWe conducted an analysis of previous adenoviral p53 (Ad-p53) treatment data in recurrent head and neck squamous cell carcinoma (HNSCC) patients to identify optimal Ad-p53 treatment methods for future clinical trials.MethodsThe analysis involved recurrent HNSCC patients treated with Ad-p53...

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Bibliographic Details
Main Authors: Robert E. Sobol, Kerstin B. Menander, Sunil Chada, Dora Wiederhold, Beatha Sellman, Max Talbott, John J. Nemunaitis
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
p53 gene therapy clinical trials
p53 immunotherapy
abscopal effect
Nanostring analysis
p53 biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.645745/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.645745/full

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