Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cells expressing sialyltransferase ST3GAL1

Oxidative damage and response to Bacillus Calmette-Guérin in bladder cancer cells expressing sialyltransferase ST3GAL1

Abstract Background Treatment with Bacillus Calmette-Guérin (BCG) is the gold standard adjuvant immunotherapy of non-muscle invasive bladder cancer (NMIBC), although it fails in one third of the patients. NMIBC expresses two tumor-associated O-linked carbohydrates: the disaccharide (Galβ1,3GalNAc) T...

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Bibliographic Details
Main Authors: Paulo F. Severino, Mariana Silva, Mylene Carrascal, Nadia Malagolini, Mariella Chiricolo, Giulia Venturi, Roberto Barbaro Forleo, Annalisa Astolfi, Mariangela Catera, Paula A. Videira, Fabio Dall’Olio
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Cancer
Subjects:
Bacillus Calmette-Guérin
Glycosylation
Sialyl T antigen
Sialyltransferase
Thomsen-Friedenreich antigen
Online Access:http://link.springer.com/article/10.1186/s12885-018-4107-1

Internet

http://link.springer.com/article/10.1186/s12885-018-4107-1

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