Down-Regulation of Nucleolar and Spindle-Associated Protein 1 (NUSAP1) Expression Suppresses Tumor and Cell Proliferation and Enhances Anti-Tumor Effect of Paclitaxel in Oral Squamous Cell Carcinoma.

Nucleolar and spindle-associated protein 1 (NUSAP1) is an important mitotic regulator. In addition to its crucial function in mitosis, NUSAP1 has recently received attention due to the interesting roles in carcinogenesis. The aim of this study was to reveal functional mechanisms of NUSAP1 in oral sq...

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Main Authors: Atsushi Okamoto, Morihiro Higo, Masashi Shiiba, Dai Nakashima, Tomoyoshi Koyama, Isao Miyamoto, Hiroki Kasama, Atsushi Kasamatsu, Katsunori Ogawara, Hidetaka Yokoe, Hideki Tanzawa, Katsuhiro Uzawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4640814?pdf=render