Mechanochemical Synthesis and Crystal Structure of the Lidocaine-Phloroglucinol Hydrate 1:1:1 Complex

Mechanochemical Synthesis and Crystal Structure of the Lidocaine-Phloroglucinol Hydrate 1:1:1 Complex

Molecular complexation is a strategy used to modify the physicochemical or biopharmaceutical properties of an active pharmaceutical ingredient. Solvent assisted grinding is a common method used to obtain solid complexes in the form of cocrystals. Lidocaine is a drug used as an anesthetic and for the...

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Bibliographic Details
Main Authors: Nancy Evelyn Magaña-Vergara, Porfirio de la Cruz-Cruz, Ana Lilia Peraza-Campos, Francisco Javier Martínez-Martínez, Juan Saulo González-González
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Crystals
Subjects:
lidocaine
phloroglucinol
crystal structure
hydrogen bond
hydration
molecular complex
Online Access:http://www.mdpi.com/2073-4352/8/3/130

Internet

http://www.mdpi.com/2073-4352/8/3/130

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