Role of Purinergic Receptor Expression and Function for Reduced Responsiveness to Adenosine Diphosphate in Washed Human Platelets.

BACKGROUND:Washing of platelets is an important procedure commonly used for experimental studies, e.g. in cardiovascular research. As a known phenomenon, responsiveness to adenosine diphosphate (ADP) is reduced in washed platelets, although underlying molecular mechanisms-potentially interfering wit...

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Bibliographic Details
Main Authors: Juergen Koessler, Stephanie Hermann, Katja Weber, Angela Koessler, Sabine Kuhn, Markus Boeck, Anna Kobsar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4725951?pdf=render