Activation of Hepatocyte Growth Factor-Met Autocrine Loop Enhances Tumorigenicity in a Human Lung Adenocarcinoma Cell Line

Activation of Hepatocyte Growth Factor-Met Autocrine Loop Enhances Tumorigenicity in a Human Lung Adenocarcinoma Cell Line

Hepatocyte growth factor (HGF) is a multifunctional cytokine with effects on the proliferation, motility, and differentiation of cells that express its receptor Met. The co-expression of HGF and Met is common among nonsmall-cell lung cancers, especially adenocarcinoma. However, the biologic consequ...

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Bibliographic Details
Main Authors: Seung Yi, Ming-Sound Tsao
Format: Article
Language:English
Published: Elsevier 2000-05-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
lung cancer
tumorigenicity
scatter factor
autocrine loop
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558600800317

Internet

http://www.sciencedirect.com/science/article/pii/S1476558600800317

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