Antifungal activity of two oxadiazole compounds for the paracoccidioidomycosis treatment.

Paracoccidioidomycosis (PCM) is a neglected disease present in Latin America with difficulty in treatment and occurrence of serious sequelae. Thus, the development of alternative therapies is imperative. In the current work, two oxadiazole compounds (LMM5 and LMM11) presented fungicidal activity aga...

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Main Authors: Franciele Abigail Vilugron Rodrigues-Vendramini, Daniella Renata Faria, Glaucia Sayuri Arita, Isis Regina Grenier Capoci, Karina Mayumi Sakita, Silvana Martins Caparroz-Assef, Tania Cristina Alexandrino Becker, Patrícia de Souza Bonfim-Mendonça, Maria Sueli Felipe, Terezinha Inez Estivalet Svidzinski, Bernard Maigret, Érika Seki Kioshima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007441