The Administration of Chitosan-Tripolyphosphate-DNA Nanoparticles to Express Exogenous SREBP1a Enhances Conversion of Dietary Carbohydrates into Lipids in the Liver of <i>Sparus aurata</i>

The Administration of Chitosan-Tripolyphosphate-DNA Nanoparticles to Express Exogenous SREBP1a Enhances Conversion of Dietary Carbohydrates into Lipids in the Liver of <i>Sparus aurata</i>

In addition to being essential for the transcription of genes involved in cellular lipogenesis, increasing evidence associates sterol regulatory element binding proteins (SREBPs) with the transcriptional control of carbohydrate metabolism. The aim of this study was to assess the effect of overexpres...

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Bibliographic Details
Main Authors: Jonás I. Silva-Marrero, Juliana Villasante, Ania Rashidpour, Mariana Palma, Anna Fàbregas, María Pilar Almajano, Ivan Viegas, John G. Jones, Montserrat Miñarro, Josep R. Ticó, Isabel V. Baanante, Isidoro Metón
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:Biomolecules
Subjects:
SREBP1
chitosan
nanoparticles
gene delivery
metabolism
<i>Sparus aurata</i>
Online Access:https://www.mdpi.com/2218-273X/9/8/297

Internet

https://www.mdpi.com/2218-273X/9/8/297

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