Effector T helper cell populations are elevated in the bone marrow of rheumatoid arthritis patients and correlate with disease severity

Abstract This study is to investigate the frequencies of T-helper (Th)22, Th17 and Th1 cells and the levels of related cytokines in subchondral bone marrow in patients with rheumatoid arthritis (RA). Bone marrow and peripheral blood samples were collected from RA, osteoarthritis (OA) patients and he...

Full description

Bibliographic Details
Main Authors: Shufeng Li, Han Yin, Kaining Zhang, Ting Wang, Yun Yang, Xinguang Liu, Xiaotian Chang, Ming Zhang, Xinfeng Yan, Yanjun Ren, Wenping Pan, Lei Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-05014-8