Two years of treatment with the recombinant grass pollen allergy vaccine BM32 induces a continuously increasing allergen-specific IgG4 response

Background: BM32, a grass pollen allergy vaccine containing four recombinant fusion proteins consisting of hepatitis B-derived PreS and hypoallergenic peptides from the major timothy grass pollen allergens adsorbed on aluminium hydroxide has been shown to be safe and to improve clinical symptoms of...

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Bibliographic Details
Main Authors: Julia Eckl-Dorna, Milena Weber, Victoria Stanek, Birgit Linhart, Robin Ristl, Eva E. Waltl, Sergio Villazala-Merino, Andrea Hummel, Margarete Focke-Tejkl, Renate Froeschel, Angela Neubauer, Rainer Henning, Thomas Perkmann, Rudolf Valenta, Verena Niederberger
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419307479