Limb-salvage surgery offers better five-year survival rate than amputation in patients with limb osteosarcoma treated with neoadjuvant chemotherapy. A systematic review and meta-analysis

Background: Osteosarcoma is the most common primary bone sarcoma. Currently, the main treatment option for high-grade osteosarcomas is neoadjuvant chemotherapy, followed by surgical resection of the lesion and adjuvant chemotherapy. Limb salvage surgery (LSS) and amputation are the main surgical tec...

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Bibliographic Details
Main Authors: Evgenia Papakonstantinou, Alexandros Stamatopoulos, Dimitrios I Athanasiadis, Efstathios Kenanidis, Michael Potoupnis, Anna-Bettina Haidich, Eleftherios Tsiridis
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Journal of Bone Oncology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2212137420300749