Precise control of SCRaMbLE in synthetic haploid and diploid yeast

Precise control of SCRaMbLE in synthetic haploid and diploid yeast

The SCRaMbLE system integrated into Sc2.0’s synthetic yeast chromosome project allows rapid strain evolution. Here the authors use a genetic logic gate to control induction of recombination in a haploid and diploid yeast carrying synthetic chromosomes.

Bibliographic Details
Main Authors: Bin Jia, Yi Wu, Bing-Zhi Li, Leslie A. Mitchell, Hong Liu, Shuo Pan, Juan Wang, Hao-Ran Zhang, Nan Jia, Bo Li, Michael Shen, Ze-Xiong Xie, Duo Liu, Ying-Xiu Cao, Xia Li, Xiao Zhou, Hao Qi, Jef D. Boeke, Ying-Jin Yuan
Format: Article
Language:English
Published: Nature Publishing Group 2018-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-03084-4

Internet

https://doi.org/10.1038/s41467-018-03084-4

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