Post-transcriptional regulation of the Sef1 transcription factor controls the virulence of Candida albicans in its mammalian host.

The yeast Candida albicans transitions between distinct lifestyles as a normal component of the human gastrointestinal microbiome and the most common agent of disseminated fungal disease. We previously identified Sef1 as a novel Cys(6)Zn(2) DNA binding protein that plays an essential role in C. albi...

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Bibliographic Details
Main Authors: Changbin Chen, Suzanne M Noble
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3486892?pdf=render