Ascending Midbrain Dopaminergic Axons Require Descending GAD65 Axon Fascicles for Normal Pathfinding

Ascending Midbrain Dopaminergic Axons Require Descending GAD65 Axon Fascicles for Normal Pathfinding

The Nigrostriatal pathway (NSP) is formed by dopaminergic axons that project from the ventral midbrain to the dorsolateral striatum as part of the medial forebrain bundle. Previous studies have implicated chemotropic proteins in the formation of the NSP during development but little is known of the...

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Bibliographic Details
Main Authors: Claudia Marcela Garcia-Peña, Minkyung eKim, Daniela eFrade, Daniela eAvila-Gonzalez, Elisa eTellez, Grant S. Mastick, Elisa eTamariz, Alfredo eVarela-Echavarria
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Neuroanatomy
Subjects:
Fasciculation
Mouse
NCAM
rat
axon guidance
Robo
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00043/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnana.2014.00043/full

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