Experimental and computational analysis of a large protein network that controls fat storage reveals the design principles of a signaling network.

An approach combining genetic, proteomic, computational, and physiological analysis was used to define a protein network that regulates fat storage in budding yeast (Saccharomyces cerevisiae). A computational analysis of this network shows that it is not scale-free, and is best approximated by the W...

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Bibliographic Details
Main Authors: Bader Al-Anzi, Patrick Arpp, Sherif Gerges, Christopher Ormerod, Noah Olsman, Kai Zinn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-05-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4447291?pdf=render