Inter-Regulation of K<sub>v</sub>4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies

Inter-Regulation of K<sub>v</sub>4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies

Background: Genetic variants in voltage-gated sodium channels (Na<sub>v</sub>) encoded by <i>SCNXA</i> genes, responsible for I<sub>Na</sub>, and K<sub>v</sub>4.3 channels encoded by <i>KCND3</i>, responsible for the transient outward curre...

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Bibliographic Details
Main Authors: Jérôme Clatot, Nathalie Neyroud, Robert Cox, Charlotte Souil, Jing Huang, Pascale Guicheney, Charles Antzelevitch
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
arrhythmia
Brugada syndrome
spinocerebellar ataxia
Na<sub>v</sub>1.5
<i>SCN5A</i>
Kv4.3
Online Access:https://www.mdpi.com/1422-0067/21/14/5057

Internet

https://www.mdpi.com/1422-0067/21/14/5057

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