Loss of MeCP2 function is associated with distinct gene expression changes in the striatum
Rett syndrome (RTT) is a neurodevelopmental disorder characterized by developmental regression beginning 6–18 months after birth, followed by a lifetime of intellectual disability, stereotyped behaviors, and motor deficits. RTT is caused by mutations in the gene encoding MeCP2, a methyl-CpG binding...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2013-11-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996113002222 |