Loss of MeCP2 function is associated with distinct gene expression changes in the striatum

Rett syndrome (RTT) is a neurodevelopmental disorder characterized by developmental regression beginning 6–18 months after birth, followed by a lifetime of intellectual disability, stereotyped behaviors, and motor deficits. RTT is caused by mutations in the gene encoding MeCP2, a methyl-CpG binding...

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Bibliographic Details
Main Authors: Ying-Tao Zhao, Darren Goffin, Brian S. Johnson, Zhaolan Zhou
Format: Article
Language:English
Published: Elsevier 2013-11-01
Series:Neurobiology of Disease
Subjects:
RTT
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996113002222